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Roos, Raymond P.

One or more keywords matched the following properties of Roos, Raymond P.

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keywords	picornavirus CNS infections
overview	Dr Roos is the Marjorie and Robert E. Straus Professor in Neurological Science in the Department of Neurology. His research program is focused on the pathogenesis of neurodegenerative diseases, especially amyotrophic lateral sclerosis, and on investigations of picornavirus central nervous system infections. He has published more than 200 papers. Dr. Roos previously served as Chair of the Department of Neurology. He has been a member of the Editorial Boards of the J. Neuroimmunology, J. Neurovirology, J. Virology, and Annals of Neurology, and presently serves on the Editorial Board of Virology and Scientific Reports. He is Associate Editor of Neurology Genetics and Editor-in-Chief of MedLink (an on-line Neurology site). He is a member of the US FDA Cellular, Tissues and Gene Therapies Advisory Committee. He formerly served as Chair of the FDA Transmissible Spongiform Encephalopathies Committee as well as the Chair of the Vaccines and Related Biological Products Advisory Committee. He was a member of the National Academy of Sciences Institute of Medicine Committee to Examine Multiple Sclerosis, American Academy of Neurology Science Committee, Amyotrophic Lateral Sclerosis (ALS) Association grant review committee, National Multiple Sclerosis Society Research Programs Advisory Committee (which he Chaired), and NIH NINDS grant review study section.

Property

Value

keywords

picornavirus CNS infections

overview

Dr Roos is the Marjorie and Robert E. Straus Professor in Neurological Science in the Department of Neurology. His research program is focused on the pathogenesis of neurodegenerative diseases, especially amyotrophic lateral sclerosis, and on investigations of picornavirus central nervous system infections. He has published more than 200 papers. Dr. Roos previously served as Chair of the Department of Neurology. He has been a member of the Editorial Boards of the J. Neuroimmunology, J. Neurovirology, J. Virology, and Annals of Neurology, and presently serves on the Editorial Board of Virology and Scientific Reports. He is Associate Editor of Neurology Genetics and Editor-in-Chief of MedLink (an on-line Neurology site). He is a member of the US FDA Cellular, Tissues and Gene Therapies Advisory Committee. He formerly served as Chair of the FDA Transmissible Spongiform Encephalopathies Committee as well as the Chair of the Vaccines and Related Biological Products Advisory Committee. He was a member of the National Academy of Sciences Institute of Medicine Committee to Examine Multiple Sclerosis, American Academy of Neurology Science Committee, Amyotrophic Lateral Sclerosis (ALS) Association grant review committee, National Multiple Sclerosis Society Research Programs Advisory Committee (which he Chaired), and NIH NINDS grant review study section.

One or more keywords matched the following items that are connected to Roos, Raymond P.

Item Type	Name
Concept	Acute Disease
Concept	Age Factors
Concept	Albumins
Concept	Amyloid
Concept	Acquired Immunodeficiency Syndrome
Concept	Antigen-Antibody Complex
Concept	Amyloidosis
Concept	Amyotrophic Lateral Sclerosis
Concept	Antibodies, Viral
Concept	Antigens, Viral
Concept	Acetylcholine
Concept	Adenoviridae Infections
Concept	Adenosine Triphosphatases
Concept	Alanine
Concept	Algorithms
Concept	Brain Diseases
Concept	Aging
Concept	Antigens
Concept	Carbazoles
Concept	Carboxypeptidases
Concept	Central Nervous System Diseases
Concept	Cerebral Cortex
Concept	Anal Canal
Concept	Epitopes
Concept	Antioxidants
Concept	Antibodies, Monoclonal
Concept	Computer Simulation
Concept	Autoimmune Diseases
Concept	Arginine
Concept	Ascorbic Acid
Concept	Costs and Cost Analysis
Concept	Histocompatibility Antigens Class II
Concept	Antilymphocyte Serum
Concept	Base Sequence
Concept	Cell Count
Concept	Cell Differentiation
Concept	Cell Nucleus
Concept	Cerebrovascular Circulation
Concept	Dipeptides
Concept	Chimera
Concept	Autoantibodies
Concept	Bacterial Proteins
Concept	Binding Sites
Concept	beta-Galactosidase
Concept	Brain Chemistry
Concept	Encephalomyelitis, Autoimmune, Experimental
Concept	Epilepsy, Temporal Lobe
Concept	Capsid
Concept	Cattle
Concept	Cell Membrane
Concept	Cerebrovascular Disorders
Concept	Child
Concept	Central Nervous System
Concept	Fecal Incontinence
Concept	Clone Cells
Concept	Cerebral Angiography
Concept	Cerebral Ventricles
Concept	Chelating Agents
Concept	Cholinesterases
Concept	Cell Cycle
Concept	Free Radicals
Concept	Cerebrospinal Fluid
Concept	Chick Embryo
Concept	Chromosome Mapping
Concept	Codon
Concept	Genetic Vectors
Concept	Communicable Disease Control
Concept	Concanavalin A
Concept	Coronaviridae
Concept	Dementia
Concept	Dentinogenesis Imperfecta
Concept	Huntington Disease
Concept	Cysteine
Concept	Coronaviridae Infections
Concept	Cross Reactions
Concept	Cryoglobulinemia
Concept	Immunoglobulin M
Concept	Distemper Virus, Canine
Concept	DNA-Binding Proteins
Concept	Cysteine Endopeptidases
Concept	Cytoplasm
Concept	Demyelinating Diseases
Concept	Immunoglobulin Fab Fragments
Concept	Immunosuppressive Agents
Concept	Sleep Initiation and Maintenance Disorders
Concept	Encephalitis, Arbovirus
Concept	Cytomegalovirus Infections
Concept	Cytopathogenic Effect, Viral
Concept	Cytotoxicity, Immunologic
Concept	Disulfides
Concept	Cathepsin B
Concept	Cerebrospinal Fluid Proteins
Concept	Child, Preschool
Concept	DNA, Recombinant
Concept	Cyclophosphamide
Concept	Encephalitis
Concept	Gene Frequency
Concept	Glycoproteins
Concept	Emergencies
Concept	Endometriosis
Concept	Enzyme Inhibitors
Concept	Equipment Contamination
Concept	Leukemia, Lymphoid
Concept	Immunoglobulin A
Concept	Immunoglobulin Fragments
Concept	Chronic Disease
Concept	Exons
Concept	Family
Concept	Cross-Sectional Studies
Concept	Disease Susceptibility
Concept	DNA
Concept	Indoles
Concept	Interferons
Concept	Introns
Concept	Motor Cortex
Concept	Multienzyme Complexes
Concept	Myasthenia Gravis
Concept	Glioma
Concept	Glial Fibrillary Acidic Protein
Concept	Killer Cells, Natural
Concept	Orthomyxoviridae Infections
Concept	Osteogenesis Imperfecta
Concept	Gliosis
Concept	Guanabenz
Concept	Ribonuclease T1
Concept	DNA, Viral
Concept	Dose-Response Relationship, Drug
Concept	Deltaretrovirus Infections
Concept	Hydrogen Peroxide
Concept	Hydrogen-Ion Concentration
Concept	Immunoglobulin Heavy Chains
Concept	Immunologic Capping
Concept	Peptide Chain Initiation, Translational
Concept	Myelin Basic Protein
Concept	Encephalomyelitis
Concept	Enterovirus Infections
Concept	Hypergammaglobulinemia
Concept	Immunity, Cellular
Concept	Immunoglobulin gamma-Chains
Concept	G(M1) Ganglioside
Concept	Leucine
Concept	Leukoencephalopathy, Progressive Multifocal
Concept	Life Support Care
Concept	Headache
Concept	Magnesium
Concept	Isoelectric Point
Concept	Methylprednisolone Hemisuccinate
Concept	Hepatitis C
Concept	Home Care Services
Concept	Membrane Proteins
Concept	Kuru
Concept	Iatrogenic Disease
Concept	Microfilament Proteins
Concept	Models, Molecular
Concept	Movement Disorders
Concept	Muscular Atrophy, Spinal
Concept	Picornaviridae Infections
Concept	Lymphotoxin-alpha
Concept	Nerve Tissue Proteins
Concept	Estrogen Antagonists
Concept	Prions
Concept	Molecular Sequence Data
Concept	Pain
Concept	Mercaptoethanol
Concept	Mice, Inbred C57BL
Concept	Middle Aged
Concept	Repetitive Sequences, Nucleic Acid
Concept	Mitogens
Concept	Muscular Atrophy
Concept	Cricetinae
Concept	HeLa Cells
Concept	Herpes Simplex
Concept	Paralysis
Concept	Respirovirus Infections
Concept	Peptide Fragments
Concept	Nerve Growth Factors
Concept	Nervous System Diseases
Concept	Myositis
Concept	Neuromuscular Diseases
Concept	Nucleotides
Concept	Nucleic Acid Conformation
Concept	Lipid Bilayers
Concept	Organophosphorus Compounds
Concept	Pedigree
Concept	Peptide Hydrolases
Concept	Peripheral Nervous System Diseases
Concept	Marek Disease
Concept	Endopeptidases
Concept	Peripheral Nervous System Neoplasms
Concept	Phenylalanine
Concept	Politics
Concept	Olivopontocerebellar Atrophies
Concept	Fatigue
Concept	Poliovirus Vaccine, Oral
Concept	Surface-Active Agents
Concept	Pepstatins
Concept	Prednisone
Concept	Plasmids
Concept	Poliomyelitis
Concept	Protein Precursors
Concept	Protein Conformation
Concept	Proto-Oncogene Proteins
Concept	Proteins
Concept	HLA Antigens
Concept	Glycine
Concept	Immunoglobulin G
Concept	Recurrence
Concept	H-2 Antigens
Concept	Registries
Concept	Residence Characteristics
Concept	Polyradiculopathy
Concept	Rodent Diseases
Concept	Quality of Life
Concept	Vision Disorders
Concept	RNA, Viral
Concept	Rectal Fistula
Concept	Scrapie
Concept	Retroviridae Infections
Concept	Ribonucleoproteins
Concept	Paraparesis, Tropical Spastic
Concept	Cadherins
Concept	Serpins
Concept	Solubility
Concept	Schwann Cells
Concept	Seasons
Concept	Sepharose
Concept	Creutzfeldt-Jakob Syndrome
Concept	Subarachnoid Hemorrhage
Concept	Respiration Disorders
Concept	Risk
Concept	RNA
Concept	Rubella
Concept	Sensitivity and Specificity
Concept	Spinal Diseases
Concept	Tetrodotoxin
Concept	Gerstmann-Straussler-Scheinker Disease
Concept	Receptors, N-Methyl-D-Aspartate
Concept	Time Factors
Concept	Togaviridae Infections
Concept	Tomography, X-Ray Computed
Concept	Superoxides
Concept	Immunoglobulin lambda-Chains
Concept	Immunoglobulin mu-Chains
Concept	Resuscitation Orders
Concept	CHO Cells
Concept	Motor Neuron Disease
Concept	Subacute Sclerosing Panencephalitis
Concept	Superoxide Dismutase
Concept	Syndrome
Concept	Oxidants
Concept	Tumor Necrosis Factor-alpha
Concept	Caenorhabditis elegans
Concept	Sequence Homology, Amino Acid
Concept	Virulence
Concept	Tamoxifen
Concept	Zoonoses
Concept	Calcium Channels
Concept	Biomarkers
Concept	Hereditary Sensory and Motor Neuropathy
Concept	HTLV-I Infections
Concept	Viral Structural Proteins
Concept	HTLV-I Antigens
Concept	Trans-Activators
Concept	Risk Assessment
Concept	PrPSc Proteins
Concept	Glutamic Acid
Concept	Reverse Transcriptase Polymerase Chain Reaction
Concept	Trazodone
Concept	Tumor Cells, Cultured
Concept	Vasculitis
Concept	Spinal Muscular Atrophies of Childhood
Concept	Mitogen-Activated Protein Kinases
Concept	Valine
Concept	Virus Cultivation
Concept	Transforming Growth Factor beta
Concept	HIV Envelope Protein gp120
Concept	Eukaryotic Initiation Factor-2
Concept	Gene Products, tax
Concept	PC12 Cells
Concept	CD8 Antigens
Concept	Cardiopulmonary Resuscitation
Concept	Zebrafish Proteins
Concept	Ion Channel Gating
Concept	Antigens, CD
Concept	Lupus Erythematosus, Systemic
Concept	Measles
Concept	Multiple Sclerosis
Concept	CD4-Positive T-Lymphocytes
Concept	AIDS Dementia Complex
Concept	Culture Media, Conditioned
Concept	Neuropeptides
Concept	Case-Control Studies
Concept	Advance Directives
Concept	Postpoliomyelitis Syndrome
Concept	Dizocilpine Maleate
Concept	Capsid Proteins
Concept	Alternative Splicing
Concept	Protein Structure, Tertiary
Concept	Meningitis, Viral
Concept	Pyramidal Cells
Concept	HIV Core Protein p24
Concept	Treatment Outcome
Concept	Myocarditis
Concept	Nerve Degeneration
Concept	Ubiquitin Thiolesterase
Concept	Consensus Sequence
Concept	RNA-Binding Proteins
Concept	Health Care Costs
Concept	Receptors, Tumor Necrosis Factor
Concept	Receptors, Interferon
Concept	Crystallography, X-Ray
Concept	Patch-Clamp Techniques
Concept	CD8-Positive T-Lymphocytes
Concept	DNA, Complementary
Concept	Disease Progression
Concept	Glucose Intolerance
Concept	beta Catenin
Concept	Molecular Chaperones
Concept	Epitopes, B-Lymphocyte
Concept	Vasospasm, Intracranial
Concept	Staurosporine
Concept	MAP Kinase Kinase Kinases
Concept	Calcineurin
Concept	eIF-2 Kinase
Concept	Immunophilins
Concept	Venous Thrombosis
Concept	Metabolic Syndrome
Concept	Excitatory Amino Acid Transporter 2
Concept	Neuroprotective Agents
Concept	Neurotoxins
Concept	Reactive Oxygen Species
Concept	Advance Care Planning
Concept	Heterogeneous-Nuclear Ribonucleoprotein Group A-B
Concept	Receptors, Tumor Necrosis Factor, Type I
Concept	Green Fluorescent Proteins
Concept	History, 21st Century
Concept	Proteasome Endopeptidase Complex
Concept	Cardiovirus Infections
Concept	Codon, Initiator
Concept	Microscopy, Confocal
Concept	Ribosomal Protein S6 Kinases
Concept	5' Untranslated Regions
Concept	6-Cyano-7-nitroquinoxaline-2,3-dione
Concept	Trinucleotide Repeats
Concept	Patient Participation
Concept	Active Transport, Cell Nucleus
Concept	Poloxamer
Concept	Nerve Growth Factor
Concept	Wnt Proteins
Concept	Postoperative Complications
Concept	Proline
Concept	Recombinant Proteins
Concept	Reference Values
Concept	Surveys and Questionnaires
Concept	Rosaniline Dyes
Concept	Serum Albumin
Concept	Severity of Illness Index
Concept	Receptor, Interferon alpha-beta
Concept	RNA, Messenger
Concept	Glycogen Synthase Kinases
Concept	Glycogen Synthase Kinase 3
Concept	Sleep Apnea Syndromes
Concept	Socioeconomic Factors
Concept	Protein Phosphatase 1
Concept	Spinocerebellar Degenerations
Concept	Glutamate Carboxypeptidase II
Concept	HEK293 Cells
Concept	Culture Techniques
Concept	Trypsin
Concept	Silver Nitrate
Concept	Spinal Cord Diseases
Concept	Viral Envelope Proteins
Concept	Vital Capacity
Concept	T-Lymphocytes, Cytotoxic
Concept	Temperature
Concept	Zinc
Concept	1-Methyl-4-phenylpyridinium
Concept	Serine Proteinase Inhibitors
Concept	Survival Analysis
Concept	Cell Death
Concept	Tuberous Sclerosis
Concept	Viral Proteins
Concept	Patient Satisfaction
Concept	Prion Diseases
Concept	Polymerase Chain Reaction
Concept	N-Methylaspartate
Concept	Amyloid beta-Peptides
Concept	Interferon-beta
Concept	Animal Rights
Concept	Lymphotoxin-beta
Concept	Presenilin-1
Concept	Calcium-Calmodulin-Dependent Protein Kinases
Concept	Receptors, Metabotropic Glutamate
Concept	Neurotransmitter Agents
Concept	Nitric Oxide Synthase
Concept	Neurodegenerative Diseases
Concept	Phosphatidylinositol 3-Kinases
Concept	Withholding Treatment
Concept	Receptor, trkA
Concept	Polypyrimidine Tract-Binding Protein
Concept	Protein Sorting Signals
Concept	Receptors, Tumor Necrosis Factor, Type II
Concept	JNK Mitogen-Activated Protein Kinases
Concept	History, 20th Century
Concept	Chromosome Disorders
Concept	Frontotemporal Dementia
Concept	RNA-Binding Protein FUS
Concept	Cell Line, Tumor
Concept	Protein Stability
Concept	Single-Chain Antibodies
Concept	TDP-43 Proteinopathies
Concept	Alzheimer Disease
Concept	Antibodies
Concept	Calcium
Concept	Calcium-Binding Proteins
Concept	Canada
Concept	Carrier Proteins
Concept	Cauda Equina
Concept	Cell Line
Concept	Cell Survival
Concept	Cells, Cultured
Concept	Chickens
Concept	Chromosome Aberrations
Concept	Cloning, Molecular
Concept	Colchicine
Concept	Complement Fixation Tests
Concept	Cytoskeletal Proteins
Concept	Disease Models, Animal
Concept	Family Health
Concept	Genetic Counseling
Concept	Immunoglobulins
Concept	Immunoglobulin kappa-Chains
Concept	Immunoglobulin Light Chains
Concept	Kinetics
Concept	Genetic Linkage
Concept	Liver Diseases
Concept	Longitudinal Studies
Concept	Luminescent Proteins
Concept	Lymphoma, Non-Hodgkin
Concept	Lysine
Concept	Magnetic Resonance Imaging
Concept	Membrane Potentials
Concept	Neoplasms
Concept	Neuroblastoma
Concept	Nuclear Proteins
Concept	Oligonucleotides
Concept	Oligoribonucleotides
Concept	Polyneuropathies
Concept	Prospective Studies
Concept	Recombinant Fusion Proteins
Concept	Retrospective Studies
Concept	Retroviridae Proteins
Concept	Sclerosis
Concept	Spinal Cord
Concept	Translocation, Genetic
Concept	Virus Diseases
Concept	Spastic Paraplegia, Hereditary
Concept	HTLV-I Antibodies
Concept	HIV Antibodies
Concept	CD4 Antigens
Concept	Tumor Suppressor Protein p53
Concept	Cytokines
Concept	Encephalopathy, Bovine Spongiform
Concept	Conserved Sequence
Concept	Age of Onset
Concept	DNA Primers
Concept	Coculture Techniques
Concept	Penetrance
Concept	Genetic Predisposition to Disease
Concept	Pick Disease of the Brain
Concept	Virulence Factors
Concept	Poly(A)-Binding Proteins
Concept	Macromolecular Substances
Concept	Proto-Oncogene Proteins c-akt
Concept	Lymphotoxin beta Receptor
Concept	Muscle Strength
Academic Article	Home ventilation for amyotrophic lateral sclerosis patients: outcomes, costs, and patient, family, and physician attitudes.
Academic Article	p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.
Academic Article	Chimeric cDNA studies of Theiler's murine encephalomyelitis virus neurovirulence.
Academic Article	Construction of a chimeric Theiler's murine encephalomyelitis virus containing the leader gene of foot-and-mouth disease virus.
Academic Article	Molecular characterization of a nondemyelinating variant of Daniel's strain of Theiler's virus isolated from a persistently infected glioma cell line.
Academic Article	Patients with amyotrophic lateral sclerosis receiving long-term mechanical ventilation. Advance care planning and outcomes.
Academic Article	Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection.
Academic Article	Human T-cell lymphotropic virus type-I infection in the severe combined immunodeficiency mouse.
Academic Article	A neutralization site of DA strain of Theiler's murine encephalomyelitis virus important for disease phenotype.
Academic Article	The regulation of gene expression in neurotrophic viruses.
Academic Article	Amyotrophic lateral sclerosis and viruses.
Academic Article	The effect of Theiler's murine encephalomyelitis virus (TMEV) VP1 carboxyl region on the virus-induced central nervous system disease.
Academic Article	What happens when mutant neuroserpins get into bad shape.
Academic Article	Theiler's murine encephalomyelitis virus-induced cardiac and skeletal muscle disease.
Academic Article	Alternative translation initiation of Theiler's murine encephalomyelitis virus.
Academic Article	Molecular determinants for virulence in coxsackievirus B1 infection.
Academic Article	The CD4-mediated immune response is critical in determining the outcome of infection using Theiler's viruses with VP1 capsid protein point mutations.
Academic Article	Influence of Theiler's murine encephalomyelitis virus 5' untranslated region on translation and neurovirulence.
Academic Article	Central nervous system cytokine mRNA expression following Theiler's murine encephalomyelitis virus infection.
Academic Article	L* protein of the DA strain of Theiler's murine encephalomyelitis virus is important for virus growth in a murine macrophage-like cell line.
Academic Article	Effect of adenovirus-mediated nitric oxide synthase gene transfer on vasospasm after experimental subarachnoid hemorrhage.
Academic Article	A Theiler's virus alternatively initiated protein inhibits the generation of H-2K-restricted virus-specific cytotoxicity.
Academic Article	The role of immunophilins in mutant superoxide dismutase-1linked familial amyotrophic lateral sclerosis.
Academic Article	The prion diseases.
Academic Article	Controlling new prion diseases.
Academic Article	Processing of wild-type and mutant familial Alzheimer's disease-associated presenilin-1 in cultured neurons.
Academic Article	Creutzfeldt-Jakob disease, new variant creutzfeldt-jakob disease, and bovine spongiform encephalopathy.
Academic Article	The role of beta-catenin stability in mutant PS1-associated apoptosis.
Academic Article	Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.
Academic Article	Novel mutations in spastin gene and absence of correlation with age at onset of symptoms.
Academic Article	Direct evidence of a role for amino acid 101 of VP-1 in central nervous system disease in Theiler's murine encephalomyelitis virus infection.
Academic Article	Cell-specific proteins regulate viral RNA translation and virus-induced disease.
Academic Article	Mixed lineage kinase 3 mediates gp120IIIB-induced neurotoxicity.
Academic Article	"Out, damned spot! out, I say!...": issues related to prion decontamination.
Academic Article	A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropathy.
Academic Article	Membrane lymphotoxin is required for resistance to Theiler's virus infection.
Academic Article	Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cells.
Academic Article	Pathogenesis of early and late disease in mice infected with Theiler's virus, using intratypic recombinant GDVII/DA viruses.
Academic Article	Failure to detect poliovirus genetic information in amyotrophic lateral sclerosis.
Academic Article	Failure to detect enterovirus in the spinal cord of ALS patients using a sensitive RT-PCR method.
Academic Article	Determinants of measles virus (hamster neurotropic strain) replication in mouse brain.
Academic Article	Molecular mechanisms of attenuation of the Sabin strain of poliovirus type 3.
Academic Article	Truncated wild-type SOD1 and FALS-linked mutant SOD1 cause neural cell death in the chick embryo spinal cord.
Academic Article	Polyclonal IgM anti-GM1 ganglioside antibody in patients with motor neuron disease and variants.
Academic Article	Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models.
Academic Article	CD4+ T cells are important for clearance of DA strain of TMEV from the central nervous system of SJL/J mice.
Academic Article	Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse.
Academic Article	Intrathecal interferon in subacute sclerosing panencephalitis.
Academic Article	Alternative translation initiation site in the DA strain of Theiler's murine encephalomyelitis virus.
Academic Article	Infectious cDNA clones of the DA strain of Theiler's murine encephalomyelitis virus.
Academic Article	Viruses and dementia.
Academic Article	Theiler's murine encephalomyelitis virus L* amino acid position 93 is important for virus persistence and virus-induced demyelination.
Academic Article	Polyprotein processing of Theiler's murine encephalomyelitis virus.
Academic Article	Different strains of Theiler's murine encephalomyelitis virus antagonize different sites in the type I interferon pathway.
Academic Article	Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.
Academic Article	Strains from both Theiler's virus subgroups encode a determinant for demyelination.
Academic Article	Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology.
Academic Article	Apoptotic and antiapoptotic activity of L protein of Theiler's murine encephalomyelitis virus.
Academic Article	The L-coding region of the DA strain of Theiler's murine encephalomyelitis virus causes dysfunction and death of myelin-synthesizing cells.
Academic Article	Restricted heterogeneity of antibody to gp120 and p24 in AIDS.
Academic Article	A subgenomic segment of Theiler's murine encephalomyelitis virus RNA causes demyelination.
Academic Article	Genetically controlled resistance to virus infections of the central nervous system.
Academic Article	HTLV-I-associated myelopathy: oligoclonal immunoglobulin G bands contain anti-HTLV-I p24 antibody.
Academic Article	Characterization of a cell culture persistently infected with the DA strain of Theiler's murine encephalomyelitis virus.
Academic Article	Autosomal dominant cerebrovascular amyloidosis: properties of peripheral blood lymphocytes.
Academic Article	Function and ultrastructure of the neuromuscular junction in post-polio syndrome.
Academic Article	Attempt to identify the agent for Creutzfeldt-Jakob disease by CF antibody relationship to known viruses.
Academic Article	Human immunodeficiency virus gp120 and p24 oligoclonal antibody in acquired immunodeficiency syndrome cerebrospinal fluid and sera.
Academic Article	Mutant SOD1 forms ion channel: implications for ALS pathophysiology.
Academic Article	Amyotrophic lateral sclerosis with antecedent poliomyelitis.
Academic Article	Spinal cord: motor neuron diseases.
Academic Article	Characterization and specificity of humoral immune responses to Theiler's murine encephalomyelitis virus capsid proteins.
Academic Article	Detection of visna virus antigens and RNA in glial cells in foci of demyelination.
Academic Article	HTLV-I hu-SCID mouse in the study of HTLV-I neurotropism.
Academic Article	The clinical characteristics of transmissible Creutzfeldt-Jakob disease.
Academic Article	Relationship of Theiler's murine encephalomyelitis viruses to the cardiovirus genus of picornaviruses.
Academic Article	Oligoclonal IgG bands in cerebrospinal fluid and serum during asymptomatic human immunodeficiency virus infection.
Academic Article	Coexistence of amyotrophic lateral sclerosis and Werdnig-Hoffmann disease within a family.
Academic Article	B-cell abnormalities in multiple sclerosis. A hypothesis.
Academic Article	Immunology of multiple sclerosis.
Academic Article	Viruses and demyelinating disease of the central nervous system.
Academic Article	Neuropathy accompanying IgM lambda monoclonal gammopathy.
Academic Article	Neurovirulence determinants of genetically engineered Theiler viruses.
Academic Article	Comparison of agar gel electrophoresis and isoelectric focusing in multiple sclerosis and subacute sclerosing panencephalitis.
Academic Article	Cerebrospinal fluid and serum oligoclonal IgG bands in rabbits with experiment allergic encephalomyelitis.
Academic Article	Light chain composition of CSF oligoclonal IgG bands in multiple sclerosis and subacute sclerosing panencephalitis.
Academic Article	Changes in concanavalin A capping of human lymphocytes with age.
Academic Article	Isoelectric focusing of IgG eluted from multiple sclerosis and subacute sclerosing panencephalitis brains.
Academic Article	A picornaviral protein synthesized out of frame with the polyprotein plays a key role in a virus-induced immune-mediated demyelinating disease.
Academic Article	Expression of human copper/zinc-superoxide dismutase inhibits the death of rat sympathetic neurons caused by withdrawal of nerve growth factor.
Academic Article	Molecular cloning and sequence determination of DA strain of Theiler's murine encephalomyelitis viruses.
Academic Article	Immunoperoxidase staining of cerebrospinal fluid IgG in isoelectric focusing gels: a sensitive new technique.
Academic Article	Silver staining of cerebrospinal fluid IgG in isoelectric focusing gels.
Academic Article	The post-polio syndrome: evaluation and treatment.
Academic Article	Antibody titer to the poliovirus in blood and cerebrospinal fluid of patients with post-polio syndrome.
Academic Article	Biochemical analysis of DA strain of Theiler's murine encephalomyelitis virus obtained directly from acutely infected mouse brain.
Academic Article	Theiler's virus as a vector for foreign gene delivery.
Academic Article	Selective knockdown of mutant SOD1 in Schwann cells ameliorates disease in G85R mutant SOD1 transgenic mice.
Academic Article	Regulation of excitatory transmission at hippocampal synapses by calbindin D28k.
Academic Article	Oligoclonal IgG in multiple sclerosis and subacute sclerosing panencephalitis brains.
Academic Article	A single amino acid change determines persistence of a chimeric Theiler's virus.
Academic Article	Oligoclonal IgA bands in multiple sclerosis and subacute sclerosing panencephalitis.
Academic Article	Isolation of an adenovirus 32 strain from human brain in a case of subacute encephalitis.
Academic Article	The effect of short-term and chronic immunosuppression on Theiler's virus demyelination.
Academic Article	The leader peptide of Theiler's murine encephalomyelitis virus is a zinc-binding protein.
Academic Article	Intracerebral distribution of infectious amyloid protein in spongiform encephalopathy.
Academic Article	The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis.
Academic Article	Theiler's murine encephalomyelitis virus neutralization escape mutants have a change in disease phenotype.
Academic Article	Isoelectric focusing studies of serum and cerebrospinal fluid in patients with antecedent poliomyelitis.
Academic Article	GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity.
Academic Article	Viral infectious complementary-DNA studies may identify nonviral genes critical to central nervous system disease.
Academic Article	Neutralizing monoclonal antibodies to Theiler's murine encephalomyelitis viruses.
Academic Article	Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons.
Academic Article	The unfolded protein response in familial amyotrophic lateral sclerosis.
Academic Article	Linkage analysis in familial amyotrophic lateral sclerosis.
Academic Article	Nucleic acid probes in the study of amyotrophic lateral sclerosis.
Academic Article	An immunological and cytogenetic investigation of tuberous sclerosis.
Academic Article	Circulating immune complexes in neurologic disease.
Academic Article	Search for retrovirus in patients with multiple sclerosis.
Academic Article	Ca2+ and reactive oxygen species in staurosporine-induced neuronal apoptosis.
Academic Article	Involvement of cardiovirus leader in host cell-restricted virus expression.
Academic Article	A protein critical for a Theiler's virus-induced immune system-mediated demyelinating disease has a cell type-specific antiapoptotic effect and a key role in virus persistence.
Academic Article	Adenoviral gene transfer of nitric oxide synthase increases cerebral blood flow in rats.
Academic Article	No correlation between aggregates of Cu/Zn superoxide dismutase and cell death in familial amyotrophic lateral sclerosis.
Academic Article	Kappa light chain predominance in serum and cerebrospinal fluid from human immunodeficiency virus type 1 (HIV-1)-infected patients.
Academic Article	Amyotrophic lateral sclerosis and life-sustaining therapy: patients' desires for information, participation in decision making, and life-sustaining therapy.
Academic Article	Huntington's disease: abnormality of lymphocyte capping.
Academic Article	Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase.
Academic Article	Mutant SOD1 knockdown in all cell types ameliorates disease in G85R SOD1 mice with a limited additional effect over knockdown restricted to motor neurons.
Academic Article	An isoelectric focusing study in herpes simplex virus encephalitis.
Academic Article	Non-productive paramyxovirus infection: Nariva virus infection in hamsters.
Academic Article	Sciatic endometriosis: a treatable sensorimotor mononeuropathy.
Academic Article	Creutzfeldt-Jakob disease: a case-control study.
Academic Article	Analysis of Theiler's virus isolates from persistently infected mouse nervous tissue.
Academic Article	CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses.
Academic Article	Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1.
Academic Article	Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants.
Academic Article	Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis.
Academic Article	An enhanced integrated stress response ameliorates mutant SOD1-induced ALS.
Academic Article	Animal extremists' threats to neurologic research continue: Neuroreality II.
Academic Article	Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function.
Academic Article	Neoplastic cauda equina syndrome: a neuroimaging-based review.
Academic Article	D. CARLETON GAJDUSEK.
Academic Article	Visuospatial Processing Deficits Linked to Posterior Brain Regions in Premanifest and Early Stage Huntington's Disease.
Academic Article	Zika Virus-A Public Health Emergency of International Concern.
Academic Article	Intermuscular coherence in amyotrophic lateral sclerosis: A preliminary assessment.
Academic Article	Gastrostomy tube placement is safe in advanced amyotrophic lateral sclerosis.
Academic Article	Long-term follow-up after surgery for simple and complex cryptoglandular fistulas: fecal incontinence and impact on quality of life.
Academic Article	S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects.
Academic Article	Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS.
Academic Article	Genetic linkage studies in Huntington disease.
Academic Article	Evidence for an early innate immune response in the motor cortex of ALS.
Academic Article	TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Academic Article	Poloxamer 188 decreases membrane toxicity of mutant SOD1 and ameliorates pathology observed in SOD1 mouse model for ALS.
Academic Article	A Masked Marauder: Hepatitis C Neuropathy.
Academic Article	Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress.
Academic Article	Single chain variable fragment antibodies directed against SOD1 ameliorate disease in mutant SOD1 transgenic mice.
Academic Article	TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection.
Grant	Combating stress in G85R ALS mice
Grant	A C. elegans model to study the disease-producing effects of dipeptide repeats from the C9ORF72 locus
Academic Article	Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS.
Academic Article	RNA-binding protein altered expression and mislocalization in MS.
Academic Article	Neurology: Genetics Year in Review.
Academic Article	A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Academic Article	Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions.
Academic Article	Kozak Similarity Score Algorithm Identifies Alternative Translation Initiation Codons Implicated in Cancers.
Concept	Zika Virus Infection
Concept	C9orf72 Protein
Concept	T-Cell Intracellular Antigen-1
Concept	Prodromal Symptoms
Concept	Calbindins
Concept	S100 Calcium Binding Protein G
Concept	Calbindin 1
Concept	Histocompatibility Antigen H-2D
Concept	Transfusion Reaction
Concept	Protein Aggregation, Pathological
Academic Article	Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons.
Academic Article	Added load increases the peak frequency of intermuscular coherence.

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